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Treatment of obesity: medical managements

R. Bolaños-Jímenez, J. Arizmendi-Vargas, S. Salazar-Marioni, C.E. Escamilla-Ocañas, K. Lozano-Andrade, H.R. Martínez¬-Menchacab, G. Rivera-Silva


Obesity is a very complex illness. It is one of the most prevalent diseases in the western world, its importance lies in the comorbidities that surround it, as well as the predisposition to cardiovascular events and other diseases that reduce life quality and expectancy. There are many factors that contribute to obesity pathogenesis; genetic, psychological, emotional, social factors, among others. Nowadays dietetic measures and changes in lifestyle are the first step in management of obesity. Because in many cases it is not enough for patients to reach their ideal weight, pharmacotherapy must be used to treat obesity and its comorbidities. Several studies have compared various drugs for losing weight, being Orlistat the only one approved by the FDA. In bariatric surgery, many surgical techniques have been developed to try to reach a balance between efficacy and safety. Although it is relatively safe, it has its own risks inherent to the procedure and its complications. It is the most effective measure to improve the global patients’ health as it not only helps people to lose weight, but also helps to have a better control of other comorbidities and lower overall mortality.

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