TY - JOUR AU - Sunita, Kumari AU - Kumar, Pradeep AU - K. Singh, D. PY - 2013/05/29 Y2 - 2024/03/28 TI - In vivo phytotherapy of snail by plant derived active components in control of fascioliasis JF - Scientific Journal of Veterinary Advances JA - Sci. J. Vet. Adv. VL - 2 IS - 5 SE - DO - UR - https://www.sjournals.com/index.php/sjva/article/view/1467 SP - 61-67 AB - <div>Fascioliasis is worldwide zoonotic disease, which caused great economic loss to human being.&nbsp;<em>In</em>&nbsp;<em>vivo</em>&nbsp;killing of&nbsp;<em>Fasciola</em>&nbsp;larva (redia and cercaria) is one of the effective methods to control of fascioliasis.&nbsp;<em>In vivo&nbsp;</em>toxicity of different binary combinations (1:1ratio) of plant derived active components such as citral, ferulic acid, umbelliferone; azadirachtin and allicin were tested against&nbsp;<em>Fasciola</em>&nbsp;larva&nbsp; (redia and cercaria) in snail&nbsp;<em>Lymnaea acuminata</em>. Mortality of larvae were observed at 2h, 4h, 6h and 8h of treatment.&nbsp;<em>In vivo</em>&nbsp;exposure of azadirachtin + allicin (1:1 ratio) was highly toxic against redia and cercaria (8h LC<sub>50</sub>&nbsp;0.007and 0.006 mg/L). Combinations of citral + umbelliferone, cirtal + ferulic acid were less toxicity against redia and cercaria larva than azadirachtin + allicin.&nbsp;<em>In vivo</em>&nbsp;use of these larvicidal active components in the binary combinations at sublethal does will be more helpful in controlling the redia/cercaria than their individual components.</div> ER -