Evaluation of fungal (Onychomycosis) in Sokoto, Nigeria

Authors

  • Aliyu Sarki Baki Department of Microbiology, Faculty of Science, Usmanu Danfodiyo University, Sokoto, Nigeria
  • Abdulrahman Bello Department of Veterinary Anatomy, Usmanu Danfodiyo University, Sokoto, Nigeria
  • Abubakar Aliyu Salihu Department of Agricultural Technology, Umaru Ali Shinkafi Polytechnic, Sokoto, Nigeria

Keywords:

Onychomycosis, Dermatophytes, Ammannawa, General Hospital, Fungal infection

Abstract

Onychomycosis is a fungal infection of the nail, which occurs worldwide with Dermatophytes as the most common causal agents although yeast and moulds are also involved. The diagnosis usually involves direct microscopy and culture to prove actual existence of onychomycosis. A total of 30 samples were tested using 20% KOH and culture plates of Sabourad Dextrose Agar (SDA) which was mixed with streptomycin as an antibiotic. A total of 80.0% samples were identified as positive by culture, among which, 46.7% were KOH positive and 33.3% were KOH negative. 20.0% were culture negative. The predominant pathogen was yeast 37.43%, followed by dermatophyte 33.33% and the moulds with 24.12% of the cases recorded. Onychomycosis was observed to be common between the age of 41-50 with the occurrence of 50%, and 50% in both male and female patients attending the hospital. The research highlighted that the yeast was a predominant pathogen in Ammannawa General Hospital Sokoto, patients should be well informed on the need to take their health and personal hygiene seriously, and also adhere to treatments. Based on the result obtained, it was recommended that people should avoid going barefoot in public places, and keep feet cool and dry. To educate patients on the need to improve their health and personal hygiene. Patients should endeavor to apply antifungal powder/spray to the inside of their shoes once a week or more, and they should also comply with all treatment protocol.

References

Alexopoulus, C.J., Mims, C.W., Blackwell, M., 2002. Introductory mycology. 4th edition. John Wiley and Sons incorporated, Singapore. 869p.

Aman, S., Nadeem, M., Haroon, T.S., 2008. Successful treatment of white subungual Onychomycosis with terbinafinetherapy. J. Coll. Phys. Surg. Park., 18, 728-9.

Baran, R., Chabasse, D., Feulide de-chaurin, M., 2001. Les Onychomycosis. II-Approche diagnostique. J. Mycol. Med., 11, 5-13.

Baran, R., Faergemann, J., Hay, R.J., 2007. Superficial white onychomycosis- a syndrome with different fungal causes and paths of infection. J. Am. Acad. Dermatol., 57(5), 879-82.

Chander, J., 2010. Textbook of medical mycology. Third new Delhi Mehta publishers. 132p.

Cheesbrough, M., 2000. District laboratory practice in tropical countries. Cambridge University press, 1-184.

Cheijinna, N.V., 2006. Potentials of the leaf extracts of Azidiarchtarindica, S. juss and Ociumgratissimum L. for the control of some potato (Solanumtuberosum L.) fungal diseases. Niger. J. Bot., 19(1), 68-73.

Chi, C.C., Wang, S.H., Chou, M.C., 2005. The causative pathogens of onychomycosis in Southern Taiwan. Mycoses, 48(6), 413-20.

Clayton, Y.M., 2006. Clinical and mycological diagnostic aspects of Onychomycosis and dermatophytosis. Clin. Exp. Dermatol., 17, 37-30.

Cursi, I.B., 2011. Onychomycosis, by Scytalidium spp.: Clinical and epidemiology in a university hospital in Rio de Janeiro, Brazil. Bra. Dermatol., 86(4), 689-693.

De Beker, D., 2009. Fungal nail disease. New Engl. J. Med., 360, 2108-16.

Elewsk, B., Tavakkol, A., 2005. Safety and tolerability of oral antifungal agents in the treatment of fungal nail disease: A proven reality. Clin. Risk Manag., 1, 299-30.

Ghannoum, M.A., Hajjeh, R.A., Scher, R., 2000. A large-scale North American study of fungal isolates from nails: The frequency of Onychomycosis, fungal distribution and antifungal susceptibility patterns. J. Am. Acad. Dermatol., 43(4), 641-648.

Gupta, A.K., Jain, H.C., Lynde, C.D., Macdonald, P., Cooper, E.A., 2000. Prevalence and epidemiology of Onychomycosis in patients visiting physicians’ offices: A multicenter Canadian survey of 15,000 patients. J. Am. Acad. Dermatol., 43, 244-248.

Hall and Brian, 2012. Saures’s manual of skin diseases (10th edition) Lippincott Williams and Wikkins publication. 33p.

Karimzadegan-Nia, M., Mir-Amin-Mohammad, A., Bouzari, N., Firooz, A., 2007. Comparison of direct Smear, culture and histology for diagnosis of Onychomycosis. Aust. J. Dermatol., 48(1), 18-21.

Kaur, R., Kashyap, B., Bhalla, P., 2008. Onychomycosis- epidemiology, diagnosis, management. Indian J. Med. Microbiol., 26(2), 108-16.

Lanternier, F., Pathan, S., Vincent, Q.B., Liu, l., Cypowj, S., 2013. Deep dermatophytosis and inherited CARD 9 deficiency. New Engl. J. Med., 396, 1704-1714.

Lorizzo, M., Piraccini, B.M., Tosi, A., 2007. A new fungal nail infection. Curr. Opin. Infect. Dis., 20, 142-5.

Manga, B.S., Oyeleke, S.B., 2008. Essentials of industrial microbiology and laboratory practical’s in microbiology 1st edition introduction, London, Blackwell publishers, Tobes publisherspp, 56-76.

Neupane, S., Pokhel, S.D., Pokhrel, B.M., 2009. Onychomucosis: A clinico epidemiological study. Nepal Med. Coll. J., 11(2), 92-95.

Ngwogu, A.C., Otokunefor, T.V., 2007. Epidemology of dermatophytoses in a rural country in Eastern Nigeria and review of literature from Africa. Mycopathologia, 164, 149-58.

Palacio, A.D., Garau, M., Gonzalez-Escalada, A., Calvo, M.T., 2000. Trends in the treatment of dermatophytosis in; Biology of dermatophytes and other keratinophilicfungi. Kushawaha, R.K., Guarro, J., Editors. Rev. Ibero Am. Micol. Bilbao, 148-58.

Paus, R., Peker, S., Sunderberg, J.P., 2008. Biology of hair and nails. In: Bolognia, J.L., lorizzo, J.L., Rapini, R.P., Editors, Dematology, 2nd edition. St. Louis, MO, USA: Mosby Elsevier publication, 979-983.

Popoola, T.O., Ojo, D.A., Alabi, R.O., 2006. Prevalence of dermatophytosis in junior secondary school children in Ogun state, Nigeria. Mycosis, 49, 499-503.

Saunte, D.M., Holgersen, J.B., Haedersdal, M., Strauss Bitsch, M., 2006. Prevalence of toenail Onychomycosis in diabetic patients. Act. Dermatol. Venereol., 86, 425-428.

Scher, R.K., 1996. Onychomycosis: A significant medical disorder. J. Am. Acad. Dermatol., 35(2), 52-55.

Scher, R.K., Baran, R., 2003. Onychomycosis in clinical practice: Factors contributing to recurrence. Br. J. Dermatol., 149, 5-9.

Singh, S., Beena, P.M., 2003. Comparative study of the different microscopic technique and culture media for the diagnosis of dermatophytes. Indian J. Med. Microbiol., 21, 21-4.

Szepietowski, J.C., 2004. Selected clinical aspects of Onychomycosis. Mikol. Lek., 11(2), 119-28.

Thomas, J., Jacobson, G.A., Narkowicz, C.K., Peterson, G.M., Burnet, H., Sharpe, C., 2010. Toenail Onychomycosis: An important global disease burden. J. Dimeal. Pharm. Therapeut., 35(5), 497-519.

Weinberg, J.M., Koestenblatt, E.K., Tutrone, W.D., Tishler, H.R., Najarian, L., 2003. Comparison of diagnostic methods in the evaluation of Onychomycosis. Am. Acad. Dermatol., 49(2), 193-7.

Westerberg, D.P., Voyack, M.J., 2013. Onychomycosis: Current trend in diagnosis and treatment. Am. Fam. Physician, 88(11), 762-70.

Published

2017-01-26

How to Cite

Sarki Baki, A. ., Bello, A. ., & Aliyu Salihu, A. . (2017). Evaluation of fungal (Onychomycosis) in Sokoto, Nigeria. Scientific Journal of Microbiology, 6(1), 142-148. Retrieved from https://www.sjournals.com/index.php/sjm/article/view/343

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