Antimutagenic activity of rosmarinus officinalis l. By Ames test

Authors

  • A. Tajehmiri Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IRAN
  • M. Ghasemi Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN
  • F. P. Sabet Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN
  • M. M. Chakoosari Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN
  • N. Abdolahzadegan Department of Microbiology, College of Basic Science, Lahijan Branch, Islamic Azad University, Lahijan, IRAN

Keywords:

Rosmarinus officinalis;Salmonella typhimurium TA100, Sodium azide, Ames test

Abstract

Plants are an important source of substanceswhich are claimed to induce anti-inflammatory and antioxidant effects. Rosemary(Rosmarinus officinalis L.) is a medicinal plant that has many uses intraditional medicine. In this study, of R. officinalis leaves extracts werescreened for their antimutagenic activity against sodium azide by Ames test.The results showed that of R. officinalis leaves extracts can inhibit mutagenicagent of sodium azide. Rosemary leaves extracts with the inhibition of 42.92%sodium azide, showed high potential in decreasing mutagenic agent.Antimutagenic activity was increased significantly when there were livermicrosome extract (S9).

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Published

2014-07-29

How to Cite

Tajehmiri, A. ., Ghasemi, M., P. Sabet, F., M. Chakoosari, M., & Abdolahzadegan, N. . (2014). Antimutagenic activity of rosmarinus officinalis l. By Ames test. Scientific Journal of Microbiology, 3(7), 78-81. Retrieved from https://www.sjournals.com/index.php/sjm/article/view/1365

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Section

Original Article